Anaconda: Bloodline (2025) brings the terror of nature’s most dangerous predators back to the screen in a gripping survival thriller. This new chapter in the Anaconda franchise elevates the stakes, blending ancient fear with modern horror as a new breed of killer anacondas emerges, threatening to wipe out everything in their path.

Plot:

The film begins in the heart of the Amazon Rainforest, where a mysterious, scientific expedition is taking place. A global research group, led by Dr. Sophia Ramirez, a seasoned wildlife biologist, has set out to study the effects of climate change on the delicate ecosystems of the Amazon. Their goal is to identify species that are evolving in response to a rapidly changing environment.